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Similar methods have been proposed in recent studies to predict complex traits and diseases using GWAS summary data (Vilhjalmsson et al.
2015 AJHG; Robinson et al. 2017 Nat Hum Behav) or age using summary data from transcriptome-wise association studies (Peters et al. 2015 Nat Comm). LD between SNPs more than d Kb away from each other are ignored.