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We did not include diagnoses as predictors because we found that we could not capture them reliably in real time. Using this structure, we could assign patients an hourly score, permitting us to also predict multiple events per patient.

We kept the highest, lowest and most deranged ( Appendix B ) vital sign recorded in the past 24 h; for laboratory tests, we took the most recent value in the past 72 h. In this hourly dataset, the outcome variable had a value of 1 if a patient experienced the outcome within 12 h of the current time point rather than only at the single time point of the event ( Appendix Fig.